Conotrane Cream 500g is used to protect the skin from moisture, irritants, chafing and contamination from bacteria or yeasts. Conotrane Cream 100g can be used for treating and preventing: Nappy rash Sores caused by sitting or lying in the same position for long periods of time (pressure sores) Urinary rash Powerful ingredients It contains two active ingredients: dimethicone and benzalkonium chloride. Dimethicone is a silicone fluid water repellent. When it is applied to the skin, it creates a barrier between the skin and water, or other water soluble irritants to the skin. Benzalkonium Chloride is an antiseptic, which is effective in protection against bacteria and fungal infections, which are often present with nappy rashes. How it works Conotrane cream works by forming a thin layer over the skin which serves as a protection and promotes healing. It can be used for treating nappy rash and for protecting the skin from moisture, irritants, and chafing.